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Interrogation of real-world data sets using the Explorys system to assess cancer rates in 300 different healthcare systems in the USA following initiation of GLP-1RA therapy in 64,230 individuals with type 2 diabetes revealed lower rates of prostate, lung and colon cancer, but higher rates of thyroid cancer [164]
2024;68: e230197 Assessment of thiol-disulfide and glutathione homeostasis after levothyroxine replacement in individuals with autoimmune or nonautoimmune hypothyroidism DOI: 10.20945/2359-4292-2023-0197 ABSTRACT Objective Thyroid hormones are known to affect the biosynthesis and degradation of antioxidant compounds, suggesting a possible link between hypothyroidism and oxidative stress
Demand is surging not only for traditional wellness applications but also for adjunctive support in chronic condition management
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The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs
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