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Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase

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All values were converted to concentration of cAMP using a cAMP standard curve performed in parallel, and data were subsequently normalized to the response of 100 nM forskolin

and other: loss of appetite, altered smell, body weight variations, myalgia, altered smell, otalgia, ophthalmologic (conjunctivitis, dry eyes), fever, changes in menstruation, urinary symptoms, dysphagia, speech disturbances (157159)

In addition to allosteric activation of G6PDH, the G6PD gene is transcriptionally activated in response to oxidative stress