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Animals were genotyped using PCR and vector-specific primers (F: ATCCACTTTGCCTTTCGCGCC, R: TTTCAAACACTGGGAAGTAACG), and primers toward Cd79b (F: GACTCTGTGGCTGCTCATCC, R: TTCAGCAAGAGCTGGGGAC) as wild-type allele control

Hosein et al., 2012) didnt display any toxicity profile related to renal dysfunction at dose-limiting toxicity (DLT)

The peptide appears to maintain organ function under stress conditions through nitric oxide system modulation and vascular protection mechanisms

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