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For anyone with hypertension, even controlled hypertension, phentermine adds cardiovascular risk that semaglutide avoids

Results showed that participants receiving semaglutide achieved a 16.1% mean reduction in BMI at 68 weeks, compared with a 0.6% increase in the placebo group

The profile is broadly comparable to, though not identical to, the side effect profiles of semaglutide and tirzepatide

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