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Taken together the current study demonstrates that ADA contributes to metabolic remodeling in RA and might mediate death of chondrocytes, proliferation of synoviocytes, differentiation of macrophages to osteoclasts and reduced differentiation of MSCs to osteoblasts and its function in vivo

The severity and specific expressions of SLE can differ significantly from one individual to another

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Hyperprolactinemia is associated with insulin resistance which improves with dopamine agonist therapy which might be related to the therapy associated weight loss and an activation of insulin signaling (5962)

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