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Pre-existing Conditions: A history of gallstones, gallbladder inflammation, or bile duct issues makes some people more vulnerable to complications
10.1136/gutjnl-2017-315193 Gut 17 GaoM.ZhangP.HuangL.ShaoH.DuanS.LiC.et al (2019)
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Hepatic oxidation of ethanol principally via alcohol dehydrogenase and the microsomal ethanol-oxidizing system enzyme CYP2E1 produces acetaldehyde and reactive oxygen species that promote lipid peroxidation, mitochondrial dysfunction and fibrogenic responses, thereby accelerating liver injury
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