"Once the news was announced that this drug had also been approved as an aid to weight loss, I wasn't surprised to find out there was going to be a shortage." Weight loss drug The NHS England and medicines regulator, the MHRA, said earlier this month "that existing stock must be conserved" for people living with diabetes
In a private-pay market, discontinuation may not mean a medicine failed clinically
The US Department of Veterans Affairs databases were used to develop a cohort of people with diabetes who initiated GLP-1RA
Acknowledgements The authors thank David Niemeyer for excellent technical assistance
While headlines often focus on blockbuster drug approvals or updated clinical guidelines (e.g., screening recommendations), GLP-1s, which were theorized in 1906 and invented in 1986, demonstrate the potential magnitude of shifts in care delivery from a single therapeutic, which has important implications for provider financial viability, patient safety and access to care
