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Additionally, PQQs antioxidant properties can help protect mitochondria from damage, further supporting their function and overall cellular health

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and (2) athymic nude mice (Balb/c, CD-1), which are thymus-deficient mice that fail to produce T cells, and the impairment of T-independent B cell maturation also occurs due to the presence of the xid mutation in the nude gene (241)

The four brain regions were acquired in overlapping subsets of the whole cohort: SM1: 52 ASD (4F/48M) and 49 TDC (12F/37M)