That gap, he added, matters for patients
It has been observed that exposure to highly palatable foods increases key neuroendocrine signals, which remodel brain reward circuits to reinforce pathological eating behaviors
GLP-1 medications (like semaglutide or tirzepatide) are designed to be injected subcutaneously (into fat) , and there are three approved injection sites: Abdomen Inject at least 2 inches (5 cm) away from the belly button Most commonly used Easy to access and rotate Consistent absorption Thigh Upper outer or front thigh Good alternative if the abdomen is sore Absorption may feel slightly slower for some people Upper arm Back of the upper arm (fatty area) Works well, especially with help Can be harder to reach on your own What matters most: Inject into fat, not muscle Rotate sites weekly Avoid scars, bruises, or irritated skin Evidence note: Studies show similar absorption and effectiveness across all approved sites when injections are done correctly
Getting Started: How to Access GLP-1 at PlexusDx PlexusDx serves all 50 states with no insurance requirement, no membership fee, and HSA/FSA eligibility
It has also been shown to reduce waist circumference, curb unhealthy cravings, and extend the patients sense of fullness after eating
