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68 , S108S114 (2014)

Glasauer, A., Sena, L

While clinical development for obesity was discontinued in 2007 after a Phase IIb trial failed to achieve its primary endpoint, the peptide remains a valuable research tool for investigating adipose tissue biology, lipolytic pathways, and receptor-independent signaling mechanisms

The major cardiovascular safety trials The SUSTAIN-6 trial enrolled 3,297 patients with type 2 diabetes and high cardiovascular risk, following them for two years on semaglutide 0.5 mg or 1.0 mg weekly versus placebo