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3.3.3 TLR9/NF-B pathway Toll-like receptor (TLR) is an early discovered class of pattern recognition receptors that play an important role in the inflammatory response to RA (164, 165)

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TP is supported by grants from the NIH (R21AG072205, R21AI097745, R01CA214913, R01HL128168, R01CA284372, and R01CA284603), US Department of Defense Peer Reviewed Medical Research Program (HT94252410100), Koch Institute-Dana Farber/Harvard Cancer Center Bridge Grant and the Rullo Family MGH Research Scholar Award