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Overdose toxicity involves severe, uncontrolled symptoms that worsen over hours and may include pancreatitis, severe dehydration, or altered consciousness

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The trial design was unusual

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Ann Int Med 164(11) June 7, 2016 doi:10.7326/M15-2650 Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)