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In addition, some putative effects of GLP-1RAs on cognitive and mental health symptoms may not require direct activity in the CNS, but rather be mediated by the actions that these medications express in the periphery across immune, endocrinemetabolic and gutbrain axis mechanisms (Fig
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Health care providers cant legally prescribe retatrutide because it is not yet FDA approved, although its being studied in stage three clinical trials by drugmaker Eli Lilly in doses up to 12 mg
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