In senescent cells, the lysosomal hydrolase, -galactosidase, which is called senescence-related -galactosidase is expressed [11]
doi: 10.1136/oem.2005.025379 Rossini M, Rizzo P, et al
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And thats before you start looking at property damage (three housefires a day in London alone are directly attributable to lit tobacco), pollution, etc caused by lit tobacco that either arent applicable to reduced risk products (Im quite sure Snus hasnt started any house fires, ever) or are massively reduced (The fact that battery fires related to e-cigs are newsworthy is testament to how rare they are notice how you dont see news stories about cigarette fires) by these products