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Symptoms of oral cancer Symptoms of oral cancer include: a mouth sore that doesn't heal a persistent, abnormal white or red patch inside the mouth or on the lip or tongue a lump or thickening in your lips, mouth, or cheek that doesn't go away a sore throat that doesn't go away voice changes trouble chewing or swallowing trouble moving your jaw or tongue loose teeth numbness in your tongue or another part of your mouth pain around your teeth or in your jaw pain or irritation in the mouth that doesn't go away unexplained weight loss swelling in your jaw a lump or mass in your neck the constant feeling that something is caught in your throat