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Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease

This is the reason many clinicians historically preferred indirect strategies such as supplying precursors like N-acetylcysteine or using intravenous glutathione in hospital settings

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However, the mRNA of the GLP-1R is present in the human cardiac atrium as others and we have already been reported (Baggio et al

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