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Since FB XW7 is frequently mutated in several solid tumors [37], such as cholangiocarcinoma, colorectal cancer, and gastric cancer, it would be interesting to investigate whether the FBXW7-ETV6 regulatory axis is broadly disrupted in these FBXW7 -mutant tumors

Louis, MO, USA) and diluted in saline to achieve a concentration of 0.08 mg/kg per infusion, a dosage routinely used and validated in operant IVSA studies in our laboratory (Ruda-Kucerova et al., 2017

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This reduction is linked to many of the physical and functional changes commonly associated with aging

Liraglutide was approved without a CVOT (Cardiovascular Outcome Trial) because authorities accepted the results from the LEADER study, designed for superiority