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214 The cardioprotective effects of semaglutide may be independent of its impact on weight, suggesting additional underlying mechanisms, including anti-inflammatory effects such as reductions in systemic inflammatory markers, which may contribute to cardiovascular benefit

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Nevertheless, it cannot be excluded that the integrative treatment we administered acted on liver function through an improved expression/synthesis of the hepatic insulin degrading enzyme (IDE), which is responsible of at least 70-80% of the clearance of circulating insulin (38)

Many have shared their positive experiences, highlighting the transformative impact of our treatments and the compassionate care they received

Endothelial cell metabolism in health and disease