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Cons: Many of the compounds require further research in independent randomized controlled trials

For viral causes, supportive care (rest, fluids, pain relief) is often sufficient

Someone current on age-appropriate cancer screening (colonoscopy, mammography, PSA testing, skin checks) has more confidence that occult malignancy is not present

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Non-antibiotic sulphonamides (furosemide, thiazides, gliclazide, celecoxib, sulfasalazine) show unlikely immunological cross-reactivity, but celecoxib and sulfasalazine remain contraindicated per their product information