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Too much estrogen being metabolized through CYP1B1 into 4-OHE1(E2) and the estrogen quinones can potentially be bad if your body has slower phase II (COMT, GSTP1, GSTM1, NQO1) enzymes.[ref][ref] The connection between smoking and estrogen-related cancers: Smoking significantly increases the risk of breast cancer and prostate cancer

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One could also use turmeric, aloe vera, and lemon juice at home to decrease pigmentation

Planning Your Treatment Our medical providers like to sit down with each patient in a consultation to truly get to know them and their needs before recommending a course of treatment