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[55] It suppresses appetite through a dual mechanism: it directly stimulates anorexigenic (satiety-inducing) neurons that express proopiomelanocortin (POMC) and cocaine-and amphetamine-regulated transcript (CART), while simultaneously inhibiting orexigenic (appetite-inducing) neurons that express AgRP and NPY
IMPORTANT SAFETY INFORMATION: Common side effects : nausea, vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, and injection-site reactions
More specifically, rotating your injection site helps reduce the risk of skin problems, such as pitting, lumps, or thickened patches (aka lipodystrophy )