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It acts on receptors in the hypothalamus and other brain regions involved in appetite regulation, decreasing hunger signals and food cravings

Clinical indications, such as dietary history, and biomarkers or investigations, such as the positive confirmation of coeliac disease, may help identify which dietary interventions are best suited to an individual (Figure 1)

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Deficiency in any of these can meaningfully impair fertility, and many Europeans are deficient in at least one