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Both organizations recommend advancing therapy when glycemic control is not achieved or maintained after 3 months (i.e., monotherapy to dual therapy, dual therapy to triple therapy and/or injectable agents [including insulin] if needed) [9, 11]

Common Model Organisms PT-141 research has utilized multiple species to establish mechanism and efficacy: Rats Primary model for sexual behavior studies (Sprague-Dawley, Long-Evans strains)

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