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The mechanism becomes especially concerning for semaglutide users who do not realize they need to dramatically increase their water intake to compensate for GI losses and suppressed thirst signals

GLP-1 agonists use a pre-filled pen that many people find less intimidating than drawing from vials

If you are an older adult on semaglutide, your protein target should be at the higher end of the range (2.0-2.2 grams per kg body weight), and creatine should be considered a baseline supplement, not an optional add-on

Additionally, if gastrointestinal side effects from semaglutide (nausea, vomiting) interfere with the ability to take levothyroxine consistently, medical guidance is needed to maintain thyroid control

If a dose is missed, administer Ozempic as soon as possible within 5 days after the missed dose