July 25, 2014
Co-localization of transcripts and translational machinery in SGs allows cells to prioritize translation of stress-related genes and sequester apoptotic proteins facilitating cellular survival [8,9,10]
Under the synergistic interaction of CGRP and NO, sustained dilation of intracranial and extracranial blood vessels occurs, promoting central sensitization and ultimately leading to the development of migraine ( 4.3 Modulating neurotransmitters and receptors The monoamine neurotransmitter system plays a significant role in the pathophysiology of migraine, contributing not only to pain modulation but also to common migraine-associated symptoms such as nausea, vomiting, and mood disorders
But those kind of faded over time
Tryptophan increased serum 5-HT levels, enhanced brain BDNF expression, reduced neuroinflammation, improved mitochondrial energy metabolism and restored gut barrier integrity by upregulating tight junction proteins (Weng et al., 2024
