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In addition, glutathione peroxidase 4, as a critical regulator of ferroptosis, facilitates the reduction in lipid hydroperoxides to lipid alcohols [116]

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For example, STI1, a highly selective small-molecule SQOR inhibitor developed by 2 S catabolism raises endogenous H 2 S levels, thereby activating cardioprotective signaling pathways such as protein sulfhydration