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Weight loss as a result of GLP-1s, when medically appropriate, can result in health benefits like lower blood pressure, a lower risk of developing type 2 diabetes, improved sleep and, in some cases, an overall improved quality of life

Autoimmune disorders: MTHFR C677T may be a risk factor for Behcet's disease, multiple sclerosis, and ankylosing spondylitis, and A1298C may be a risk factor for multiple sclerosis

The HOGA1 gene is predominantly expressed in the kidney and the enzyme is localized to the mitochondria

[DOI] [PubMed] [Google Scholar] 101.Simo R, Hernandez C

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