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Prefer a signal that closely mirrors your body's own rhythm

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glutathione's antioxidant activity may dampen this response Mechanism 4: Thyroid Hormone Metabolism Support Thyroid hormone conversion - the transformation of inactive T4 (thyroxine) to active T3 (triiodothyronine) - is performed by iodothyronine deiodinase enzymes (DIO1, DIO2, DIO3), which are selenoproteins that depend on the glutathione/thioredoxin antioxidant system for their activity and regeneration

Cortex 22 , 469481 (2012)

Akt and eNOS are proteins that work farther down the same signaling route