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Neoadjuvant chemotherapy for operable breast carcinoma larger than 3 cm: a unicentre randomized trial with a 124-month median follow-up

Specifically, the synergistic action of metformin and simvastatin reshaped glioma metabolism, curbed malignant proliferation, promoted apoptosis, and demonstrated superior anti-tumor effects both in vitro and in vivo compared to individual administration of metformin or simvastatin

Individuals with known structural heart disease, previous arrhythmias, family history of sudden cardiac death or inherited arrhythmia syndromes, or concurrent use of medications that prolong the QT interval should undergo thorough cardiac assessment

Jezova D, Jurankova E, Mosnarova A, Kriska M, Skultetyova I

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