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If, for example, this deficit is secondary to other primary pathologies that have already been diagnosed and require significant pharmacological treatments, the administration is done directly into the vein to obtain absolute and immediate effectiveness

Competing interests Nik Krajnc: has participated in meetings sponsored by, received speaker honoraria or travel funding from BMS/Celgene, Janssen-Cilag, Merck, Novartis, Roche and Sanofi-Genzyme and held a grant for a Multiple Sclerosis Clinical Training Fellowship Programme from the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)

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