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The skeptical cardiologist, like most physicians, has always assumed that weight loss, whether accomplished by diet/exercise, bariatric surgery, or drugs would benefit obese patients since it lowers blood pressure, cholesterol and blood sugar levels

Calcitonin measurements are used less frequently for early diagnosis of MTC today, largely replaced by genetic tests for diagnosis of hereditary MTC

"Just losing the weight and being able to keep it off with the use of these medications is definitely worth the risk of not being regulated by the FDA," Delp said

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Harvard Health Publishing also explored this topic after a 2025 study published its results