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As for Polyphenol Booster, it contains: Pomegranate extract (375mg) , shown in a 2022 study to increase short-chain fatty acids and regulate GLP-1 secretion at 375mg doses,32 while a 2025 study found that pomegranate in general can help proliferate beneficial bacteria, including Akkermansia 33 Grape seed extract (275mg) , which produces a significant prebiotic effect on Akkermansia , as in a 2021 study that used 200mg doses34 Green tea extract (225mg) , which also favors Akkermansia proliferation,35 potentially at doses as low as around 50mg in a 150lb human (as suggested by mouse studies)36 All very well-dosed to support Pendulums probiotic supplements

Will our nation treat obesity as a chronic disease worthy of sustained medical management, or as a lifestyle issue that individuals are expected to manage largely on their own

One major study published in early 2025, which followed over 351,000 adults, found no statistically significant increase in the long-term risk of thyroid cancer for those taking GLP-1 medications compared to those on other diabetes drugs

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