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10.1002/ijc.28148 55 MaubachG.LimM

148,149 Proliferating cancer cells exhibit aerobic glycolysis, leading to a shift in glucose carbon away from the TCA cycle, which results in the increased use of glutamine to fuel anabolic processes to support rapid cell growth with increased NADPH and ammonia generation

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The viability of erastin-treated cells whose myristoylation had been inhibited by IMP-366, was rescued by deferoxamine (DFO), ferrostatin-1 (Fer-1), and liproxstatin-1 (Lip-1) (Fig

However, the reverse Warburg effect does not apply to all tumors (221)