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Main Dual agonism of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors (GLP-1R and GIPR, respectively), in the form of once-weekly injectable tirzepatide, is highly effective for treating people living with obesity and type 2 diabetes, resulting in greater weight loss than GLP-1R agonism alone 2

Cagrilintide has a larger molecule (37 aa, MW 3,924 Da) and dissolves more slowly

Ichimiya T, Okubo Y, Suhara T, Sudo Y

Tesamorelin is administered daily, typically in the morning, which effects becoming more observable within just a few weeks

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