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576,577 Superoxide dismutase (SOD) was the first antioxidant enzyme discovered and remains the only enzyme known to eliminate superoxide anion (O 2 ) in mammals, playing a crucial role in combating oxidative stress

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This is consistent with previous studies that found transcription factors play an important role in biotic and abiotic stress responses 30,39

Pharmaceutical Nanosuspensions with Improved Bioavailability Nanosuspensions prepared by sonication show a significant improved pharmacological bioavailability