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However, knockout mice were not protected from hepatic steatosis induced by a high fat diet, potentially due to decreased fatty acid oxidation caused by a compensatory increase of ACC2, which in turn inhibited mitochondrial -oxidation [58]

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Many of these side effects are a direct result of its mechanism of action, and patients are not advised to initiate on a high dose of Ozempic

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Intermediate phase: weeks two through four More noticeable changes typically emerge during weeks two through four