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Appetite hormones shift, satiety signals change, energy expenditure adapts, cravings can intensify, and the brains reward pathways do what they were designed to do: push you back toward your prior weight

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In addition, aberrant Ca 2+ signaling causing mitochondrial dysfunction can adversely affect neurotransmitter signaling and lead to excitation/inhibition imbalance [94, 97, 98]

Healthcare providers treat bezoars with medication to dissolve it, or if necessary, surgery to remove it

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