Hyperphosphatemia, a hallmark of CKD-MBD, triggers FGF-23 elevation to promote urinary phosphate excretion, but progressive renal failure limits compensatory mechanisms, exacerbating phosphate retention ( 2.2 Skeletal abnormalities Chronic kidney disease-mineral and bone disorder induces heterogeneous bone disorders, ranging from high-turnover osteitis fibrosa to low-turnover adynamic bone disease (ABD)
No strong evidence but biological plausibility
The ranges below reflect what has been reported in published research and clinical practice they are informational only and do not constitute a dosing recommendation
Accessed 9/7/2021, Hart RJ
At the species level, there was an increase in the abundance of Intestinibacter sp900540355 , Phocaeicola plebeius , Pseudoruminococcus massiliensis , Rikenella microfusus , Barnesiella intestinihominis , CAG-452 sp000434035 , Bacteroides fragilis , Turicibacter sanguinis , and Alistipes communis and decrease in the Bariatricus comes , Faecalibacterium prausnitzii , Intestinimonas butyriciproducens , Parvimonas sp001553085 , Gemella morbillorum and Finegoldia magna [208]
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