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Younger et al

Given the insufficient number of studies, the level of evidence was classified as Expert opinion

About four in ten adults ages 50 to 64 and 65 and older say they have heard a lot about GLP-1 drugs, compared to about one-third of adults ages 30-49 (32%) and one in six adults ages 18-29 (17%)

From these, we selected for estimation parameters that were not available from literature and that are most directly associated with the dynamics of the GSH and GSSG concentrations ([GSH] and [GSSG], respectively), for which we had available experimental data

New studies indicate that urinary histamine profiles and their metabolites might be valuable biomarkers but these methods remain under validation