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This was predominant in the male Gclc L-KO mice and was not rescued with Nrf2 deletion (Fig

A byproduct of oxidation is the creation of free radicals, which are unstable molecules that can damage cell DNA and potentially cause permanent mutations

Biochem Biophys Res Commun 2007

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Such studies have shown that antibiotic administration might increase the effectiveness of L-DOPA therapy, indicating that gut microorganisms affect metabolism and the effectiveness of the drug (Hashim et al., 2014)