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The common functioning mechanisms of various mushroom polysaccharides that involves the activation of the above three activities are the activation of neutrophil, cytotoxic, cytokines (interferons, interleukins, and colony-stimulating factors), natural killer cells, monocytes, dendritic cells, and macrophages (Wasser, 2011)

Dong et al

In fact, patients with irritable bowel syndrome (IBS), a typical bowel disease in which stress is associated with gastrointestinal symptoms, reportedly had more than 16-fold increase in the incidence of IBD 54

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