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Nonlinear methods like ANN offer several benefits, particularly their ability to flexibly model intricate and nonlinear relationships, as a rule, they showed better performance than PLS [16]

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This means that instead of considering the H 2 O 2 molecules as being presented individually and in rapid succession to the active sites, it is necessary to consider the whole network of nH 2 O 2 molecules hydrogen bonded to water and each other, spreading out from the enzyme