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Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

For example, GPER promotes the phosphorylation of AMPK, enhancing cellular adaptation to energy deficits and improving metabolic efficiency [170, 221, 222]

More clinical evidence exists for the use of riboflavin as prophylaxis against migraine headaches 66

Qiu et al., 2021

2019 (Lancet HIV, n=61) Phase II investigator-initiated trial in HIV-NAFLD: about 32% liver-fat reduction and lower fibrosis-progression rate versus placebo at 12 months