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Strengths of the present meta-analysis are the inclusion of all CVOTs published by 10 December 2021, the very large number of participants, the high quality of the trials which minimizes the risk of bias, and the absence of significant heterogeneity in most analyses, which ranged from absent to low or moderate

However, patients taking this medication may notice changes in bowel habits and stool characteristics due to altered gastrointestinal transit time and digestive processes

But this policy misses the mark and risks doing real harm