The majority of research has been conducted on animals, and human studies are still needed to draw definitive conclusions
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A larger randomized, placebo-controlled intervention trial (the SELECT study) in more than 35,000 middle-aged and selenium-replete men, randomized to receive selenium (in the form of selenomethionine, 200 g/day) and/or vitamin E supplementation, was halted because of concerns regarding an increased risk of type 2 diabetes mellitus with selenium and increased risk of prostate cancer with vitamin E (84, 85)
Because, again, dont forget, if youve got over-methylation, and you take a methyl product, can make actually people feel worse and not better
Fukuzumi, Shunichi