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Treatment of newborn rats with L-buthionine sulfoximine (BSO), an irreversible inhibitor of GCLC, leads to hepatic abnormalities including mitochondrial dysfunction 10

By mimicking the action of a natural hormone, they deftly regulate appetite, creating a prolonged sense of fullness that helps curb cravings and overeating tendencies

To activate Cre recombinase and induce Gclc deletion in tumour pieces from Gclc f/f Rosa26 creERT2 MMTV-PYMT mice, female mice were intraperitoneally injected with tamoxifen (Sigma-Aldrich, T5648) at 50160 mg kg 1 once daily for 5 consecutive days

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