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Moreover, curcumin greatly alleviated the suppression of hippocampal neurogenesis in BTBR mice, resulting in increased neurogenesis and proliferation of neural progenitor cells (47)

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Abdominal irradiation induces intestinal epithelial cell apoptosis and that treatment with GH or IGF1 treatment can significantly inhibit this effect (Mylonas et al., 2000), while there is study also suggests that GH shows radioprotective effect through increasing local IGF1 level and counteracting cell apoptosis (Mahran et al., 2015)

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This finding is further supported by decreased expression of glutathione peroxidase and cystine/glutamate antiporter, as well as increased levels of MDA, suggesting the occurrence of LPO in injured kidney tissues