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15 Damage-associated molecular pattern (DAMP) species released into the circulation, such as nuclear fragments and mitochondrial DNA (mtDNA), appear to recruit inflammatory cells via the innate immune system as the livers attempt to remove necrotic cell debris and promote the livers recovery phase

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Dihexa is orally bioavailable in animal models, with cognitive effects comparable to subcutaneous injection a property virtually absent among conventional neuropeptides that require intranasal or injectable delivery (PMID: 23055539)