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Bioavailability is lower with oral forms, potentially requiring higher milligram doses to achieve equivalent effects

Tongue swelling could indicate an allergic reaction or angioedema, which is listed as a potential hypersensitivity reaction in the SmPC

In vitro pharmacology (EC 50 ) Evaluation of the agonist activity of compounds 1 23 at the mouse GLP-1 receptor endogenously expressed in TC6 cells, was determined by measuring their effects on cAMP production using the HTRF detection method (performed by Cerep S.A., catalogue 2015, ref

Both Wegovy and Ozempic use gradual dose-increasing schedules to minimise side effects