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Ethics statement The animal study was reviewed and approved by Xiangya Hospital Central South University

Gorrab A, Pagano A, Ayed K, Chebil M, Derouiche A, Kovacic H, et al

This study suggests that liraglutide may effectively reduce body weight and mitigate hyperphagia caused by MC4R deficiency, providing a basis for its potential therapeutic application in patients with MC4R -deficient obesity

Branded versions of semaglutide and tirzepatide such as Wegovy, Ozempic, or Zepbound undergo extensive clinical trials and FDA review for safety, efficacy, and consistency

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